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The success of Kalydeco, a drug to treat cystic fibrosis, has been decades in the making — since the discovery of the gene associated with the disease. The time from gene discovery to successful drug may be shortening, but there are only a handful of drugs like Kalydeco on the market.

The lessons of the final deal come down to this: Washington is very nearly broken. Next up? Finishing the work this agreement postponed.

The drama over the fiscal cliff and the familiar up-against-a-deadline dysfunction of Congress have largely overshadowed the leave-taking of some Capitol Hill originals. A look at the legacies of Barney Frank, Ron Paul, Dennis Kucinich, Olympia Snowe, Richard Lugar and Joe Lieberman.

The former Soviet citizens who flooded into Israel two decades ago have changed the country's demographics, helped strengthen the economy and played a significant role in the general rightward shift of the Israeli electorate.

At its height, American tennis consistently fielded the world's top male players. Now that American dominance is gone, so too are many of the top U.S. men's tournaments. They're moving overseas, snapped up by groups offering more lucrative payouts in a sport enjoying huge global appeal.

In an interview with NPR, Pelosi said the GOP has "made enormous contributions to the success of our country." But she added: "There are many members in the Republican caucus who do not believe in government. And bless their hearts, they act upon their beliefs."

Page had one of the biggest-selling singles ever with her version of "The Tennessee Waltz."

California Democrat Eric Swalwell, one of the youngest new members of Congress, defeated a 40-year incumbent for his seat. But his first challenge in Washington might be getting people to pronounce his name correctly.

The Hardy family goes back generations in a tiny neighborhood called Gerritsen Beach in Brooklyn. For them, Superstorm Sandy has created an extended family reunion. Not only is their small, barely livable home bursting with family members — the storm brought an emotional change, as well.

The Magnificent Century, which explores the Ottoman Empire in all its 16th-century glory, is a big hit in Turkey. But the country's prime minister, an Islamist, is angry that the program focuses on palace intrigue involving the sultan and his harem.