McConnell has served in the top GOP spot for 18 years, putting Kentucky in the spotlight on numerous high-profile debates in that time.
Now, McConnell’s colleagues have chosen current Senate Minority Whip John Thune to step into the position -- rejecting the candidate who sought to most closely align himself with President-elect Donald Trump, Florida’s Rick Scott.
Still, Thune is sounding a note of unity as Republicans take the reins of all branches of government. This is the incoming majority leader on CNBC.
"But we've got to be able to find a way to work together as a coalition with President Trump to enact an agenda, because we really have probably a two year window. You never know what's going to happen in the next election. We have one every even-numbered year. And so we've got a narrow window," he said.
In a statement following his election, Thune said, “This Republican team is united behind President Trump’s agenda, and our work starts today.”
McConnell praised the choice for his successor.
"John Thune’s election is a clear endorsement of a consummate leader. The confidence our colleagues have placed in John’s legislative experience and political skill is well deserved," the Kentucky senator said, adding, Thune "will take the reins with a tremendous opportunity to lead this transformation, and Senate Republicans stand behind him, ready to get to work.”
But Thune hasn’t always had an easy relationship with Trump, most notably after whipping colleagues to thwart efforts by Trump allies to block certification of President Biden’s win in the 2020 race.