Kentucky (21-8, 8-7 Southeastern Conference) got 12 points from Clara Strack and 11 apiece from Teonni Key and Tonie Morgan.
The Cats made 24 of 52 (46.2 percent) from the floor, including 7 of 19 (36.8 percent) from behind the arc. The Tigers hit 22 of 57 (38.6 percent) from the field, but just 2 of 11 (18.2 percent) from three-point range.
Auburn (14-15, 3-12) scored the first two points of the game, but Hassett hit back-to-back threes to give UK a 6-2 lead. Layups from Morgan and Key closed a 10-0 run that stretched the lead to eight. After an Auburn free throw, Strack scored underneath, then made two free throws to extend the lead to 14-3.
The Tigers scored four in a row before Strack connected on the baseline to build the lead to 16-7. Auburn scored four in a row before a Key free throw and a Morgan layup gave the Cats a 19-11 advantage, which would be the score after one quarter.
Kentucky started the second quarter with baskets from Key and Morgan, leading by 12. Auburn scored the next five before Kaelyn Carroll hit back-to-back threes to extend the lead to 29-16. The Tigers scored five in a row to get within eight before a Jordan Obi bucket made it 31-21. The teams would trade baskets for the remainder of the quarter and Kentucky led 35-27 at the half.
In the third quarter, Auburn scored first before a Key layup. After the Tigers scored again, Strack, Morgan and Strack scored at the rim to build the lead to 43-31. Auburn scored four in a row before a Hassett three and a Morgan free throw made it 47-35, Cats.
The Tigers scored to get within 10, but Key drove to the basket for a layup that gave Kentucky a 49-37 lead. Auburn hit a free throw, but a Hassett three gave UK a 52-38 lead after three quarters.
Obi hit two free throws to get the fourth-quarter scoring started. Hassett hit her fifth three of the game to extend the lead to 57-38 before Auburn scored its first points of the period. Two Key free throws stretched the lead to 19 again before Auburn went on a 10-2 run to get within 11.
A Strack basket ended the streak, but Auburn closed the game on a 6-0 run to provide the final margin of victory.
Kentucky closes the regular season on Sunday, hosting third-ranked South Carolina inside Historic Memorial Coliseum. Tipoff is set for 2 p.m. and the game can be seen on SEC Network Plus.