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A Russian named Grigory Perelman, is credited with helping solve a famous 100-year-old math problem. Both the problem and the man who solved it are a bit of a puzzle.

The latest report cards from top U.S. retailers show shoppers are making fewer purchases and fewer trips to stores. But when they check out, they tend to spend more because things cost more.

Also: Thatchers funeral set for April 17; Kerry and Netanyahu claim progress on Mideast peace; some Plains states getting b buried by spring snow; Louisville men win national basketball championship.

Also: President Trump will talk up his infrastructure ideas today in Washington; Japanese lawmakers permit the Emperor to abdicate; and the Pittsburgh Penguins win Game 5 of the Stanley Cup final.

Also: Vice President Biden talks to Florida Jewish leaders about the Iran deal; a search continues for the killers of an Illinois officer; and a lost sheep is finally sheared of 88 pounds of fleece.

Also: Syria's military says it controls nearly all of Aleppo; a New Orleans jury convicts the man who killed former NFL player Will Smith; and a cyclone makes landfall in India.

New Zealand's bird of the year is not a bird. The long-tailed bat, or pekapeka-tou-roa, won by a wide margin.

Mohsen Fakhrizadeh, believed to have led Iran's military nuclear program, died from wounds after an attack, causing outrage in Iran and raising international concerns over potential retaliation.

Amazon and Walmart are in a battle for low-income shoppers. Now Amazon is cutting the $10.99 monthly rate on its Prime membership to $5.99 for people who receive government assistance.

Xylazine, a veterinary anesthetic commonly referred to as “tranq,” has recently made its way into the illicit drug supply as a drug adulterant to enhance the effects of fentanyl, a potent opioid that can be lethal even in small amounts. The new drug combination has resulted in a 1,127% increase in xylazine-positive overdose mortalities in the American south from 2020 to 2021, and results in other problematic health effects including tissue necrosis. Now two researchers at the University of Kentucky will use a $2.65M grant to study how xylazine and fentanyl change the brain’s signaling pathways. This week Dr. Greg talks with Cassandra Gipson-Reichardt, associate professor in the University of Kentucky College of Medicine’s Department of Pharmacology and Nutritional Sciences, who is conducting the study with fellow professor Terry Hinds, Jr.