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The defeat of the measure by a 54-46 vote — six votes shy of the number needed to clear the Senate — marks a major setback for gun-control advocates

Ricin is a naturally occurring toxin found in castor beans. You can get sick by eating beans. But purified ricin can be made pretty easily and used for no-good.

Margaret Thatcher was laid to rest in a funeral attended by dignitaries from around the globe as well as Queen Elizabeth and Prince Philip on Wednesday. It's the first funeral of a British politician attended by the Queen since Sir Winston Churchill's in 1965.

They don't want to offend Hispanic voters, but they don't want to turn off the GOP base either, says Ron Bonjean, a former Republican leadership aide. And competing for Hispanic votes is not a top priority for the sizable number of Republican rank and file who still see the bill as amnesty.

Melissa Block talks to Ari Shapiro about President Obama's remarks after the Senate rejected a proposal to expand background checks before gun purchases.

Writer-director Sebastian Junger remembers his friend and colleague Tim Hetherington, killed in April 2011 by mortar fire in the Libyan city of Misrata.

The highest-grossing music festival in the world happens in a city struggling to stay afloat.

As the day dawned, officials said an estimated 5 to 15 people were killed and more than 160 were wounded. It was feared those numbers might go higher. The cause of the fire that led to the explosion at a plant near Waco is under investigation.

Also: an animated interview with David Foster Wallace; the self-publishing trend; and a spirited defense of Justin Bieber.

Clues are still being sifted — most notably, perhaps, from video that shows a man setting down a bag and leaving the scene. No arrests have been made. Thursday morning, President Obama is at an interfaith service in Boston where the victims will be remembered.